Stem Cells: From Bench to Bedside

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Edition: 2nd
Format: Hardcover
Pub. Date: 2010-09-01
Publisher(s): World Scientific Pub Co Inc
List Price: $223.00

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Summary

Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.

Author Biography

Ariff Bongso, PhD, MSc (Canada), DSc (Sing), FRCOG (ad eundem) (UK), DVM, FSLCOG, DSc (hon) (Sri Lanka), is Research Professor at the Department of Obstetrics and Gynaecology of the Yong Loo Lin School of Medicine, National University of Singapore. For his contributions to human assisted reproduction and stem cell biology, he was conferred the Singapore National Science Technology Award in 1988 and the National Science Award in 2002; the Asian Innovation Award (Gold) from the Far East Economic Review in 2002; the Excellence for Singapore Award in 2003; and the ASEAN Outstanding Scientist Award in 2005. He holds several patents and has over 460 publications and conference presentations. He is on the editorial boards of Stem Cells (USA), Stem Cells Reviews and Reports (USA) and Human Fertility (UK) and is a member of the International Academy of Human Reproduction in Israel. Eng Hin Lee, MD, FRCS (Canada), FRCS (Ed), FRCS (Glas) FAMS (Sing) is currently the Executive Director of the Biomedical Research Council, Agency for Science, Technology and Research (A*STAR). He is a Professor in Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and Senior Consultant in Orthopaedic Surgery at the National University Hospital, and the KK Women's and Children's Hospital, Singapore. He leads the Stem Cell Biology Group in the NUS Tissue Engineering Program. His research on Stem Cells and Tissue Engineering in musculoskeletal tissues has won him numerous international and national awards. He currently sits on the boards of many professional and scientific bodies and is a member of the editorial boards of several medical and scientific journals. He has several patents and has edited and written many books and book chapters as well as over 150 publications in refereed journals and over 250 conference papers.

Table of Contents

Forewordp. v
Forewordp. ix
Prefacep. xiii
List of Contributorsp. xix
Human Embryonic Stem Cell Characterization: Similarities and Differences between Cell Lines and Sourcesp. 1
Molecular Principles Underlying Pluripotency and Differentiation of Embryonic Stem Cellsp. 23
Differentiation of Human Embryonic Stem Cells to Cardiomyocytesp. 87
Suspension and Simulated Microgravity Cultures of Human Embryonic Stem Cellsp. 113
Large Scale Culture of Pluripotent Stem Cells for Therapyp. 127
Human Embryonic Stem Cell-derived Tissue Transplantation Therapy: Clinical Hurdlesp. 155
Challenges of Taking Embryonic Stem Cells from Bench to Clinicp. 185
Induced Pluripotent Stem Cellsp. 209
Control of the Human Pluripotent Cell Cyclep. 235
Uses of Umbilical Cord Blood Stem Cellsp. 253
Human Umbilical Cord Wharton's Jelly Stem Cells: Their Nature, Properties and Benefitsp. 303
Derivation of Hepatocytes from Human Umbilical Cord Lining Epithelial Stem Cellsp. 323
Fetal Mesenchymal Stem Cellsp. 339
From Stem Cells to Neurons: Translating Basic Science into Preclinical Animal Validationp. 369
Stem Cells of the Liver: Basic Science and Clinical Applicationsp. 409
Stem Cells of the Eyep. 431
Human (Skeletal) Mesenchymal Stem Cells: Basic Biology and Clinical Applications for Bone Tissue Regenerationp. 457
Cartilage Repair with Stem Cellsp. 477
Ligament and Tendon Repair with Adult Stem Cellsp. 503
Stem Cells in Human Skin: Basic Science and Applicationsp. 523
Germline Differentiation from Stem Cellsp. 557
Stem Cells of the Human Uterus: Derivation, Characterization and Uses of Endometrial Stem Cellsp. 583
Stem Cells in Cardiac Tissue Engineeringp. 611
Stem Cell Science and Human Induced Pluripotent Stem Cells: Fine-Tuning the Ethical Issuesp. 637
Stem Cells: New Scientific Developments, Familiar Ethicsp. 665
Indexp. 685
Table of Contents provided by Ingram. All Rights Reserved.

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